Normal Abnormal Values of Hemoglobins


 Normal reference values can vary by laboratory, but are generally within the following ranges.

  • Adults
  • Child (Hb F):
  • Hgb A: 95-98%
  • Hgb A2: 1.5-3.5%
  • Hgb F: 0.8-2.0%
  • Hgb S: 0%
  • Hgb C: 0%.
  • greater than 6 months: 1-2%
  • 6 months: 8%
  • newborn (Hgb F): 50-80

 

What abnormal results mean:   

  • The presence of significant levels of abnormal hemoglobins may indicate:
  • Hemoglobin C disease
  • Rare hemoglobinopathy
  • Sickle cell anemia
  • Thalassemia is an additional condition under which the test may be performed.

Special considerations: 

A blood transfusion within the previous 12 weeks can produce falsely normal or abnormal results.

Abnormal results:

Abnormal reference values can vary by laboratory, but when they appear within these ranges, results are usually associated with the conditions that follow in parentheses.

Hgb A2:

  • 4-5.8% (thalassemia minor)
  • under 2% (Hb H disease)

 Hgb F:

  • 2-5% (thalassemia minor)
  • 10-90% (thalassemia major)
  • 5-35% (Heterozygous hereditary persistence of fetal hemoglobin, or HPFH)
  • 100% (Homozygous HPFH)
  • 15% (Homozygous Hgb S)

 Homozygous Hgb S:

  • 70-98% (Sickle cell disease).

 Homozygous Hgb C:

  • 90-98%(Hgb C disease)

 

 

 






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