AGAROSE VS CAPILLARY ELECTROPHORESIS


To get correct and reliable results in any diagnostic technique, much more in electrophoresis, the Specificity as important as Sensitivity. 

Agarose electrophoresis ensure higher specificity (98.9%) than Capillary (93.7).

See: Lissoir B et al (2003): Ann Biol Clin (Paris).;61(5):557-62

       Christopher R. McCudden, PhD et al: Am J Clin Pathol 2008;129:451-458 

 

Also, paraprotein classification, which compared the CZE immunosubtraction method to immunofixation electrophoresis (IFE) on agarose, showed 100% agreement. Certain dysproteinemias involving beta lipoprotein were in partial concordance due to the inability of the CZE procedure to detect this component. 

See: Carl R. Jolliff and Cynthia R. Blessum (1997): ELECTROPHORESIS,18, 1781–1784

See also:

Yvonne Henskens et al (1998): Clinical Chemistry, 44, 6, 1184-1190  

Zhaohai Yang,et al (2007): Am J Clin Pathol 128(2):293-9






active³ 4.9 · © 2000 - 2013 IPS Ltd · Disclaimer