To get correct and reliable results in any diagnostic technique, much more in electrophoresis, the Specificity is as important as the Sensitivity.
Agarose electrophoresis ensures higher specificity (98.9%) than Capillary (93.7).
Lissoir B et al (2003): Ann Biol Clin (Paris).;61(5):557-62
Christopher R. McCudden, PhD et al: Am J Clin Pathol 2008;129:451-458
Also, paraprotein classification, which compared the CZE immunosubtraction method to immunofixation electrophoresis (IFE) on agarose, showed 100% agreement. Certain dysproteinemias involving beta lipoprotein were in partial concordance due to the inability of the CZE procedure to detect this component.
Carl R. Jolliff and Cynthia R. Blessum (1997): ELECTROPHORESIS,18, 1781–1784
Yvonne Henskens et al (1998): Clinical Chemistry, 44, 6, 1184-1190
Zhaohai Yang,et al (2007): Am J Clin Pathol 128(2):293-9